Frasier and Niles play amateur sleuths after discovering a skull in their boyhood home.

Back in 1964, the Crane brothers slipped into their elementary school science class to borrow a skull for their backyard production of “Hamlet.” At the time, they were living in a house their parents rented from Mr. and Mrs. Lasskopf. Nearly 40 years later, Niles and Frasier hear that their former home is on the market. They dream of turning the place into a bed and breakfast, and invite Martin to join them when they go to inspect the property.

Their surly ex-landlord Lasskopf is still there. Although the house proves unsuitable as an inn, Frasier and Niles happily recall writing “The Crane Brothers Mysteries” in the living room. They also remember placing a “memory box” of interesting items from their childhood under the floorboards, but Lasskopf refuses to let them look for it. Undaunted, Niles and Frasier sneak back into the home that evening. While searching for their memory box, they unearth a skull – and immediately assume they’ve stumbled upon evidence of a murder.

Meanwhile, Roz doesn’t know how to tell her daughter, Alice, that her hamster has died, so she has Martin babysit while she goes out to buy a new one. Over at the Lasskopf house, Frasier and Niles deduce that Lasskopf killed his wife and buried her remains under the floorboards. At Frasier’s condo, Martin gently tells Alice that her pet went to Hamster Heaven, and Roz thanks him for handling the situation. After having Lasskopf arrested, Niles and Frasier are aghast to find a program from “Hamlet” in the memory box. Instantly, they remember that the skull was a prop in their play, and they slink off to clear Lasskopf.