After celebrating her 80th birthday, Joan Rivers takes the concept of "bucket list" to new highs (and lows) by compiling her "F*%k It" list. While Joan ticks off her "F??k It" list (she twerks, has a naked casting call, takes drugs, enters a "Best Ball" contest, makes a sex tape and pushes Melissa over the edge when she brings the Zombie Apocalypse into their home), Melissa juggles motherhood and her busy career. Melissa ends her long-distance relationship, and is hit with scandal close to home when she's betrayed by her best friend, Lynne.

Joan always goes the extra mile when she enlists celebrities to join her antics. This season Kris Jenner, Carmen Electra, Tara Reid, Christina Milian, Mike White, Giuliana Rancic, Penn & Teller, Margaret Cho, Marissa Jaret Winokur, French Stewart, and Lisa Rinna join the fun.

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